What 80 Years of LSD Can Teach Us

From counterculture to cutting-edge research, LSD has shaped how we think about consciousness, creativity, and human potential for more than 80 years.

Recent RAND research estimates that over 10 million U.S. adults have microdosed psychedelics like LSD and psilocybin in the past year, while emerging studies are beginning to explore its safety profile and potential across areas like depression and women’s health.

We are still early in the modern LSD era. With less than 100 years since its synthesis, we are uncovering its full potential, how to optimize microdosing approaches, how to weigh benefits and risks, and how it may fit into the future of mental health, creativity, and personal transformation.

📣 Join Our Live Webinar

Join the Microdosing Collective and Third Wave for a live conversation with Zach Leary on June 25, author of Your Extraordinary Mind, host of the Psychedelics Then and Now podcast, and son of Timothy Leary, for a cultural deep dive into LSD microdosing in the 21st century where science, history, and lived experience meet.

We will explore its resurgence, what research is beginning to show, why set, setting, and sustainability matter, and what it means to treat psychedelics as a long-term practice rather than a trend.

📆 Thursday, June 25th, 2026
⏰ 10:00 AM PST | 1:00 PM EST
💬 60 minutes, including a live Q&A
💻 Online | Free to attend

Can’t make it live? Register anyway and we’ll send you the full recording!

What We’ll Explore:

• The arc of LSD from Hofmann to the 1960s to today’s resurgence

• Why LSD is re-emerging now and what it reveals about modern life

• What research is beginning to show about LSD microdosing and its effects

• Why set, setting, and sustainability are essential for psychedelic use at any dose

• What it means to treat psychedelics as a long-term practice

🍄 Join our Giving Circle

If you’ve benefited from microdosing, or believe in a future where people can legally and safely access it, we invite you to become a monthly supporter.

Our Giving Circle makes it easy to support microdosing legalization through small, consistent contributions. We’re incredibly grateful for your support as we continue growing this movement through advocacy, education, research, and community.

- With love from team Microdosing Collective 🍄

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DISCLAIMER: This newsletter is intended for educational and informational purposes only and should not be considered a replacement for professional medical advice. Always consult your healthcare provider before making changes. The Microdosing Collective does not promote the use of any illegal substance. Please be aware that the use, possession, and distribution of psychedelic substances are illegal in many countries and could lead to legal consequences.